As noted in this article, almost 90% of equine laminitis cases are believed to be endocrine in nature—that is, associated with insulin dysregulation (a term that generally includes hyperinsulinemia, equine metabolic syndrome and insulin resistance); Pituitary Pars Intermedia Dysfunction (once called equine Cushing’s disease or syndrome); or a combination of these abnormalities.
“Nowadays, we think of PPID and the ID cluster (HI, IR, EMS) as being separate phenomena, but that some horses/ponies can develop both,” said Philip Johnson, BVSc, MRCVS, professor of equine internal medicine at the College of Veterinary Medicine at the University of Missouri. “Although on its own, PPID probably doesn’t cause laminitis, having PPID and ID in the same animal makes laminitis a possibility.”
So, what are the causes in the remaining 10% of laminitis cases? These…